ERG and prostate neoplasm: Finally, in this ERG+ group, the “triple hit” combination was found in 22 prostate tumors: none of the GS = 6 tumors, 5 of 50 (10%) GS = 7 and 17 of 38 GS ≥ 8 (44.8%) prostate tumors showed alterations in the protein expression of all three genes.