Finally, the “triple hit” IHC phenotype (ERG expression/ SLC45A3 loss/ PTEN loss) was not detected in any of the GS = 6 prostate tumors, and was found in 5/103 (4.8%) GS = 7, and in 17/78 (21.8%) GS ≥ 8 prostate tumors (Figure 2). Here, PTEN is linked to prostate neoplasm.