Day 16 represents a breakpoint when MC32A tumor growth resumed in a majority of CEA.Tg mice treated with mGITRL-FP alone (Figure 2C), whereas antitumor efficacy was maintained with vaccine and mGITRL-FP treatment resulting in complete regression in 68% of CEA.Tg mice (Figure 1) and a significant improvement in survival (Figure 2G). This evidence concerns the gene CEACAM5 and neoplasm.