We further compared the correlation between TTF1 and DLL3 protein in cell lines, and NKX2-1 and DLL3 mRNA in cell lines, an additional SCLC patient cohort [40] and a cohort of glioblastoma patient samples [41] and found significant correlations in each dataset (Figure 4E). This evidence concerns the gene NKX2-1 and small cell lung carcinoma.