For the pulmonary metastases of ACC, we found that the nodules’ SUVs correlated well with CXCR4 scoring by IHC and levels of CXCR4 mRNA, suggesting that 64Cu-plerixafor can be used to quantify CXCR4 expression on tumors. This evidence concerns the gene CXCR4 and adrenal cortex carcinoma.