Moreover, a study characterizing the exomes of 31 non-small cell lung cancer (NSCLC) genomes found 4 missense mutations in PIK3C2B: c.349C>G (P117A), c.3542G>T (C1181F), c.3623A>G (H1208R) and c.4407G>T (L1469F). This evidence concerns the gene PIK3C2B and non-small cell lung carcinoma.