TP53 and Fanconi anemia: In LUAD, the genes were enriched in Pyrimidine metabolism, Ribosome biogenesis in eukaryotes, p53 signaling pathway, HTLV-I infection, RNA transport, Base excision repair, Homologous recombination, Fanconi anemia pathway, Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation, DNA replication, Nucleotide excision repair and Mismatch repair (Fig 6B and S2 Table).