These preliminary data suggest that cells harbouring the wild-type haplotype have a better response to glucocorticoid showing a more pronounced decrease of proinflammatory cytokines, including cytokines and chemokines associated with asthma and Th2 lung inflammation, as IP-10 and RANTES [51,52], MIP-1β[53], IL-6, IL-8 [54], and eotaxin [55,56]. This evidence concerns the gene CCL4 and asthma.