Considering that isolated monoclonal NAb to gB and gH can effectively interfere with both FB and EC infection [32,33,34,35,36,37], antibodies to these envelope glycoproteins may significantly contribute to both the FB- and EC-specific NAb responses measured for HCMV seropositive (HCMV+) individuals in vitro. The gene discussed is ERVW-1; the disease is infection.