Pro-angiogenic growth factors secreted by tumor cells, such as angiopoietin-2, epidermal growth factors (EGFs), fibroblast growth factors (FGFs), vascular endothelial growth factors (VEGFs), and platelet-derived growth factors (PDGFs) can stimulate angiogenesis around tumor tissue [6]. The gene discussed is ANGPT2; the disease is neoplasm.