We chose three different cellular lines, KATO III, AGS and the inducible clone AGS-AC1: the first one is from a metastatic site, poorly differentiated, with high expression of TFF1 protein; the second one is from a gastric intestinal type, highly differentiated adenocarcinoma, with very low expression of TFF1; the last one is an hyper-expressing inducible clone of AGS. This evidence concerns the gene TFF1 and adenocarcinoma.