Regarding the correlation of peripheral WBC and TME, pretreatment tumor specimens with a high intraepithelial CD8+ TIL expression had a significantly lower baseline WBC count (p = 0.014) compared to patients with no or only low infiltration, whereas there was no significant correlation between WBC and peritumoral (stromal) CD8+ TIL (p = 0.17) (Figures 2C,D). The gene discussed is CD8A; the disease is neoplasm.