BRAF and thyroid cancer, nonmedullary, 2: BRAF point mutations are the most common gene mutations in thyroid cancer, occurring in 45% of papillary thyroid carcinomas (PTC), 20–40% of poorly-differentiated thyroid carcinomas (PDTC), and 30–40% of anaplastic thyroid carcinomas (ATC) (8, 9), while they are rarely seen in follicular thyroid carcinomas (FTC).