ICAM1 and neoplasm: Indeed, similar to the induction of ICAM-1 expression in murine lungs by LPS in our previous study36, around 50% of live lung cells from TM CAR T-treated mice stained positive for murine ICAM-1 (Fig. 5c), compared to much lower expression and percentage of ICAM-1 stained cells from non-tumor bearing mice (<5% in untreated lungs vs. >50% after LPS treatment, Fig. 6 a, b in Kang et al. 36), or tumor-xenografted mice without T cell treatment (<5%, Fig. 5c).