We performed simulations of peptide-MHCI presentation of HIV-derived peptides for up to 72 hours post infection using the combined model, and compared four controlling alleles HLA-B*58:01, B*57:01, B*27:05 and B*44:037–11 and four non-controlling alleles, HLA-B*18:01, B*35:03, B*07:02 and B*55:0115,26. This evidence concerns the gene HLA-B and infection.