S100B and infection: In this study, where immunogenicity is explored using sequence binding preferences of HLA alleles in combination with protein kinetics and peptide processing steps, we predict that the controlling alleles considered by Borghans et al. 28 present almost exclusively Gag peptides in high abundance at 24 hours post-infection, whereas B*35:03 has a more varied repertoire, including peptides from Pol, Nef and Env (Fig. 6).