KLK3 and posterior cortical atrophy: The higher rates of testing in older men are consistent with the findings of other studies of UK GP8–10 although not with the age distribution of men agreeing to participate in the ProtecT study, the latter being in close agreement with the male population age distribution, with the majority of men being younger than 60 years.17 These findings suggest that interest in PCa screening is not concentrated in the older age groups, and that the greater incidence of testing in older men is likely to arise due to other diagnostic indications for the PSA test.