KLK3 and posterior cortical atrophy: Melia et al, studying 469 159 men aged 45–84 years, reported an annual rate of 6% over 1999–2002 for England and Wales, with an annual rate of 2% in the absence of symptoms.8 Williams et al, studying 126 716 men aged 45–89 years and without a prior diagnosis of PCa, found that 6.2% of these men received a PSA test during 2007.9 This study concluded that testing was more prevalent in older men, more southern areas of the UK (especially Wales) and areas of lower deprivation.