In some neuropathology studies, 2N tau protein does not stain tau inclusions in CBD post-mortem brain tissue [73], and blots of sarkosyl-insoluble tau from both PSP and CBD lack 2N Tau isoforms [74], though we note studies using different conditions have been also detect 2N tau in CBD and PSP. This evidence concerns the gene MAPT and supranuclear palsy, progressive, 1.