By gating on the F480+ CD11b+ MHC-IIhi CD206lo M1-like and F480+ CD11b+ MHC-IIlo CD206hi M2-like populations (Fig 4A), we found that TTI-621 dramatically increased the phagocytosis of in vitro expanded, as well as of ex vivo purified, lymphoma cells compared to control Fc (Fig 4A and 4B). The gene discussed is ITGAM; the disease is lymphoma.