In our study, we showed that CDK7 inhibition suppressed NF‐κB signalling pathway activation and p65 nuclear translocation in RA FLS (Figs 3 and 4), indicating that reduction of IL‐1β/IL‐6 secretion by CDK7 inhibition might be due to NF‐κB signalling pathway blockage. This evidence concerns the gene IL1B and rheumatoid arthritis.