The frequency distribution of CYP19 rs.2414096 alleles in PCOS and controls were 0.36 for A and 0.64 for G in comparison to 0.51 and 0.49 in controls for A and G respectively (p=0.02) (OR=1.8 95% CI=1.113-2.896). The gene discussed is CYP19A1; the disease is polycystic ovary syndrome.