CYP19A1 and Ovarian Hyperandrogenism: As SNP rs.2414096 of CYP19 gene is located in an intron, different forms of it can affect regulatory sequences, therefore the rs.2414096, “A” allele could be associated with normal function of different hormones which can protect the ovaries from developing PCOS, while a decline in the activity of these hormones could be linked to the “G” allele with further ovarian hyperandrogenism and subsequent PCOS (17).