ANGPTL8 and type 2 diabetes mellitus: Serum levels of ANGPTL8 were significantly higher in subjects with IFG, IGT, CGI, and T2DM when compared to subjects with NGT (1.07 ± 0.52 ng/mL, 0.92 ± 0.57 ng/mL, 1.23 ± 0.48 ng/mL, and 0.85 ± 0.67 ng/mL versus 0.38 ± 0.25 ng/mL, P < 0.001) (Table 1).