Although 7.4% of our patients had plasma PLP < 20 nmol/L and 23.5% of our patients (particularly those in advanced CKD stage and those undergoing hemodialysis) were taking vitamin B-6 supplements which led to the mean plasma PLP level having an adequate status (>20 nmol/L) and levels in a large variation, significant associations between vitamin B-6 and CRP, IL-1β, and IL-10 existed in our CKD and hemodialysis patients. This evidence concerns the gene IL1B and chronic kidney disease.