The most serious form of infection-induced haemolysis was reported to be due to dengue haemorrhagic fever, which required blood transfusions.28 41 As dengue infection is prevalent in the GMS74 and CNSHA might be under-reported, the benefits of G6PD screening might also be applicable to G6PD-deficient individuals with CNSHA. Here, G6PD is linked to Dengue hemorrhagic fever.