MAPK8 and Insulin resistance: OxLDL signaling in adipocytes induces adipocyte insulin resistance through the activation of IKK, JNK, and NF-kB, even independently of further ROS formation [95], and this may involve the interaction of oxLDL receptor with CD36, resulting in CD36 association with the Src family tyrosine kinases Fyn and Lyn upstream of JNK [96].