Furthermore, the expression of proapoptosis protein Bax was significantly upregulated in high concentration groups (80 μg/ml for PANC1 cells and 10 μg/ml for BxPC3 cells), and the expression of antiapoptosis protein Bcl2 was downregulated in the same groups (Figure 6), demonstrating that curcumin promoted apoptosis of PCa cells. The gene discussed is BCL2; the disease is posterior cortical atrophy.