ALB and exocrine pancreatic carcinoma: Besides their natural derivatives, synthetic defensin analogs may be designed for greater anticancer efficacy: Du et al. demonstrated that recombinant tailored defensin (DF-HSA) comprising human β-defensin-2 (DF) and human serum albumin (HSA) was more effective than natural β-defensin at curbing the proliferation of K-Ras-mutant MIA PaCa-2 cells and suppressing the growth of a pancreatic carcinoma xenograft (53).