Initially, we analyzed blood parasitemia and, as shown in Figure 1A, mice treated with anti-LFA-1 (green) antibody had increased blood parasitemia when compared with the group only immunized and treated with the control isotype (red), whereas mice treated with anti-VLA-4 (yellow) had a parasite burden similar to the immunized (red). The gene discussed is ITGAL; the disease is parasitic infectious disease.