Furthermore, our results that overexpression of TCF21 inhibits migration are in accordance with in vitro studies in colorectal cancer cell lines (Dai et al., 2016, 2017) as well as siRNA suppression of endogenous TCF21 in renal progenitor cells which increased migration (Plotkin and Mudunuri, 2008). This evidence concerns the gene TCF21 and colorectal cancer.