In addition, the levels of MST1 were lower (p = 0.026) in stage IV CRC patients (132.49 ± 138.36 ng/ml), which exhibit distant metastasis, than the mean value in stage I, II and III CRC patients (266.44 ± 275.82 ng/ml) (Fig. 3c). The gene discussed is MST1; the disease is colorectal carcinoma.