This inflammation was dependent on the adoptive transfer of HEL-specific CD4+ T cells, since vitritis was not detected in control sTg-IRBP:HELlo (data not shown) or sTg-IRBP:HELhi (Fig. 3A) mice that did not receive HEL-specific CD4+ T cells prior to infection with MCMV-HEL. The gene discussed is CD4; the disease is infection.