At the peak of vitritis (day 7 post-infection), there was a marked difference in the number of antigen-specific CD4+ T cells infiltrating the retinas of sTg-IRBP:HELlo and sTg-IRBP:HELhi mice, where the latter contained ~50-fold more HEL-specific CD4+ T cells (Fig. 3C; p < 0.0001). The gene discussed is CD4; the disease is infection.