CD4 and infection: HEL-specific CD4+ T cells were detected in the pooled samples of choroid/RPE of both sTg-IRBP:HELhi mice and nTg controls on day 4 (Fig. 4D) and day 7 (Fig. 4C,D); however, the extent of infiltration was greater and longer lasting in sTg-IRBP:HEL recipients than in nTg mice (Fig. 4D; days post infection p = 0.045; nTg vs sTg p = 0.02).