However, levels of BALF lactate dehydrogenase (a marker for cell death; see online supplementary figure 4A), uric acid (see online supplementary figure 4B) and ATP (see online supplementary figure 4C) in influenza-treated mice were unaltered by neutrophil depletion, and administration of allopurinol (to impair uric acid synthesis) or suramin (a broad spectrum P2 receptor antagonist) failed to diminish IL-1β release (see online supplementary figure 4D). The gene discussed is IL1B; the disease is influenza.