TARDBP and amyotrophic lateral sclerosis: Future studies comparing the morphology of TDP-43 inclusions in larger cohorts of clinically and genetically well-characterised FTLD cases without ALS are needed in order to compare and refine the current TDP-43 classification scheme, and determine whether all FTLD cases without ALS or type C morphology can be characterised into one homogenous FTLD-TDP subtype characterised by rounded TDP-43 inclusions.