GAL and neoplasm: NOD/SCID mice that received splenocytes from untreated control mice or α-gal(-) N-ly, α-gal(+) N-ly, and α-gal(-) PDAC-ly vaccinated KO mice developed large tumors, whereas α-gal(+) PDAC-ly vaccinated mice exhibited significantly slower tumor growth (Fig 6A and 6B).