GAL and neoplasm: Furthermore, strong disruption of PDAC cells in tumor lesions was observed in α-gal(+) PDAC-ly vaccinated KO mice, whereas a large number of viable PDAC cells was found in tumor lesions of α-gal(-) N-ly/α-gal(+) N-ly vaccinated KO mice and α-gal(-) PDAC-ly vaccinated KO mice.