Previous investigations on genes such as HLA-A, HP, CFH, IL1B, IL12B, IL12RB1, IL4R and HPR [4, 5, 6, 7, 8, 9, 10, 11, 12] revealed associations between the polymorphisms in some of these genes with infectious diseases including HIV, viral hepatitis, malaria and tuberculosis. This evidence concerns the gene IL12RB1 and infectious disease.