36 Grugni Grugni G G Sartorio Sartorio A A Crino Crino A A Growth hormone therapy for Prader-willi syndrome: challenges and solutions Growth hormone therapy for Prader-willi syndrome: challenges and solutions Ther Clin Risk Manag Ther Clin Risk Manag 2016 2016 12 12 873 873 881 881 27330297 27330297. This evidence concerns the gene GH1 and Prader-Willi syndrome.