WNT5A and Sepsis: A recent study shows that Wnt5a-induced IL-6 and concurrent inhibition of extracellular signal-regulated protein kinase 1/2 activity could inhibit the differentiation of monocyte-derived myeloid dendritic cells, suggesting that Wnt5a may act as a candidate mediator for the CD14+/++CD16+ monocyte accumulation in patients with sepsis [63].