CD8A and cervical carcinoma: In the case of cervical cancer, there is one study by Chen and colleagues who revealed increased levels of circulating CD8+CD25+CD127dim/negFoxP3+ lymphocytes in women with invasive cervical carcinoma (stage IA-IIB) and CIN3 compared to healthy counterparts, with no significant difference between CIN3 and invasive cancer detected [16].