When considering the relation between the level of apoptosis and differential expression of CD95 in CD4+ and CD8+ T cells, one can notice that it is within the CD8+ T cell subset where the correlation between the relative amount of CD95-expressing cells (CD3+CD8+[CD95+/CD95−] ratio) and the level of Anx binding with CD95+ lymphocytes was found in the CIN/CC patient group only, whereas for CD4+ T lymphocytes this correlation was detectable in the control group as well (r > 0.7). This evidence concerns the gene CD8A and cervical squamous intraepithelial neoplasia.