Our previous study confirmed that biatractylolide has a significant effect on reducing the activity of AChE in the brain and improving the memory ability of mouse dementia induced by aluminum trichloride [18]; moreover, biatractylolide can significantly reduce cholinesterase activity in model rats and improve the behavior and memory of AD model rats induced by Aβ1−40 [19]. Here, BCHE is linked to Alzheimer disease.