Light microscopy-based quantification of the percentage of infected cells and the infection index (which combines the proportion of infected cells and the number of parasites per cell) showed that treatment with eATP decreased the parasite load in wild-type macrophages, while the parasite load remained high in cells from NLRP3−/− and Caspase1/11−/− mice (Figure 1). The gene discussed is NLRP3; the disease is infection.