The epitopes that have so far been targeted in molecular imaging studies include Cathepsin B, epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), Claudin-1, and tyrosine-protein kinase Met (c-Met) for the enhanced detection of colonic adenoma, and EGFR and vascular endothelial growth factor (VEGF) for CRC. The gene discussed is EGFR; the disease is colorectal carcinoma.