In IPF and ARDS, the levels of MMP-1, -3, -7, -8, -9, -13, and/or -28 in lung tissue are increased, correlating with disease severity (Selman et al., 2000; Henry et al., 2002; Fligiel et al., 2006; Craig et al., 2015). Here, MMP1 is linked to idiopathic pulmonary fibrosis.