MUC5AC and Keratoconjunctivitis sicca: The price of this formulation was set at 27 yen per 0.35 ml, based on the price of diquafosol sodium (Diquas®), which was developed by Santen as a de novo treatment for dry eye by increasing mucin secretion via activation of P2Y2 receptors in corneal epithelium (Nakamura et al., 2012).