NR3C2 and Anxiety: Optogenetic activation of DR and MR nuclei revealed a unexpectedly fast component of MR-hippocampal activation (Varga et al., 2009) and the involvement of these nuclei in shaping of different behaviors, such as anxiety (Ohmura et al., 2014), sleep regulation (Ito et al., 2013) and memory consolidation (Wang et al., 2015).