Because competition between SEMA3D and VEGF leads to inhibition of VEGF-dependent activation of neuropilins51, and VEGFC and VEGFD are associated with lymphangiogenesis52, we would expect that SEMA3D would play a role in lymphangiogenesis inhibition rather than angiogenesis; however, its precise molecular function in uterine cancer remains to be elucidated. The gene discussed is VEGFD; the disease is uterine cancer.