In co-immunoprecipitation pull-down experiments, 47 efficiently pulls down both cellular DCN1 and DCN2 proteins in a dose-dependent manner in cell lysates from the KYSE70 esophageal cancer cell line (Fig. 4b) that has high DCN1 expression (Supplementary Fig. 4a). The gene discussed is DCUN1D1; the disease is esophageal cancer.