CDKN1A and Miyoshi myopathy: In MM, Leotta et al. [21] showed that when MM cells were transfected with miR-125a-5p mimics, expression of TP53 gene and p53 pathway-related genes such as BAX, MDM2, CDKN1A, and GADD45 was downregulated, and p53 was found to be a direct target of miR-125a-5p.