IQGAP2 and diffuse astrocytoma: Similarly, the mRNA expression of IQGAP2 was high in diffuse astrocytoma (fold change = 3.78), oligodendroglioma (fold change = 2.05), anaplastic oligoastrocytoma (fold change = 4.83) (Fig 6A) and anaplastic oligodendroglioma (fold change = 2.77) (S3 Table).