IQGAP3 and colorectal cancer: Likewise, in TCGA datasets for colorectal cancer, IQGAP3 expression was found to be higher in colon adenocarcinoma (fold change = 2.03) and rectal adenocarcinoma (fold change = -2.25) but, not in colon mucinous and rectal mucinous adenocarcinoma (Fig 5D).