The TCGA brain cancer datasets (GBM, LGG and GBMLGG) also showed higher expression of IQGAP2 in glioblastoma (fold change = 4.80), astrocytoma (fold change = 3.55), oligodendroglioma (fold change = 2.54) and oligoastrocytoma (fold change = 2.80) (Fig 6B). Here, IQGAP2 is linked to brain cancer.