These data are in keeping with the reports that autophagy contributes to the enrichment and survival of cancer stem cells.24, 25 It has been reported that mTORC1 signaling is essential for the regulation of hematopoietic stem cell quiescence,26 but the effect of iASPP on cancer stem cell properties in NSCLC still needs to be further elucidated. Here, PPP1R13L is linked to non-small cell lung carcinoma.