GBP2 and breast carcinoma: Previous work demonstrated that Drp1-dependent mitochondrial fission regulates metastasis of breast cancer cells.17 We found that IFN-γ treatment resulted in mitochondrial elongation and induction of GBP2 expression, with little change in Drp1 expression or Mfn1 and Mfn2 in the indicated cells (Supplementary Figure 2b).