CXCL10 induces neuronal apoptosis in SIV and West Nile virus encephalitis.18, 19 In addition, it promotes cancer cell apoptosis in human papillomavirus-associated cervical carcinoma.43 We recently demonstrated that MuV significantly induces CXCL10 expression in mouse testicular somatic cells.12 The present study showed that MuV-induced CXCL10 in Sertoli cells triggered the apoptosis of male germ cells in a paracrine manner. The gene discussed is CXCL10; the disease is cancer.