Notably, Zika virus infection induces CXCL10 production in mouse testicular somatic cells and leads to leukocyte infiltration in the testes, resulting in orchitis.31, 32 These results suggest that CXCL10 production might be involved in the pathogenesis of the testes after MuV and Zika virus infection. This evidence concerns the gene CXCL10 and Zika virus infectious disease.