Moreover, we previously showed that among those Koreans with sporadic or autosomal recessive severe SNHL with significant residual low-frequency hearing that went away mostly during early childhood and early adolescent years, 11.2% carried the variants of this gene, suggesting that DFNB8, rather than DFNB10, is a more important TMPRSS3-related phenotype in Koreans [8]. Here, TMPRSS3 is linked to sensorineural hearing loss disorder.